Search results for "pigment epithelium-derived factor"

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Role of Ocular Angiogenic Factors in the Development of Neovascular Age-Related Macular Degeneration

2020

Abstract Age-related macular degeneration (AMD) is a progressive degenerative eye disease. Neovascular age-related macular degeneration (nAMD) is the advanced form of AMD characterised by abnormal growth of newly formed blood vessels in chorioidea which typically involves fluid accumulation in the retina or retinal haemorrhage, retinal epithelial detachments, hard exudate or subretinal scars. The process of angiogenesis is controlled by ocular angiogenic factors, which have enabled the development of different treatment options aimed at these factors. This review aims to compile the available information about the most commonly identified ocular angiogenic factors, uncovering their role in …

0301 basic medicinepigment epithelium-derived factormedicine.medical_specialtyMultidisciplinaryvascular endothelial growth factorgenetic structuresGeneral interestScienceangiogenic factorsQbiomarkersMacular degenerationmedicine.diseaseeye diseases03 medical and health sciences030104 developmental biology0302 clinical medicineAge relatedOphthalmology030221 ophthalmology & optometrymedicinesense organsProceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences.

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